MARCOPRIM BOLUS (1X4)

Broad-Spectrum Antibacterial Therapy for Livestock

Marcoprim Bolus is a potent veterinary antibacterial medication formulated with Co-trimoxazole, a synergistic combination of Sulfamethoxazole and Trimethoprim. This dual-action formula provides broad-spectrum coverage against a wide variety of bacterial infections in cattle, buffaloes, goats, and sheep. It targets both gram-positive and gram-negative bacteria, making it ideal for respiratory infections, gastrointestinal diseases, urinary tract issues, and wound infections in livestock. When animals show signs of fever, cough, diarrhea, or poor appetite due to infection, Marcoprim Bolus offers fast-acting, reliable treatment. Trusted by veterinarians and livestock owners alike, this bolus supports quick recovery, reduces animal stress, and helps maintain herd productivity.

What is Co-trimoxazole?
Co-trimoxazole is a fixed-dose combination of two antibiotics:

• Sulfamethoxazole – A sulfonamide that inhibits bacterial growth by blocking folic acid synthesis.
• Trimethoprim – Enhances the antibacterial effect by inhibiting a different step in folic acid production.

Together, they create a synergistic action that stops the multiplication of bacteria and accelerates infection control.

Recommended For
Marcoprim Bolus is used in veterinary medicine to treat and manage:

• Respiratory infections (pneumonia, bronchitis)
• Diarrhea and enteritis
• Urinary tract infections
• Mastitis in cattle and buffaloes
• Post-surgical infections and abscesses
• Septicemia and general bacterial infections
• Metritis and reproductive tract infections
• Infections in wounds, cuts, or skin lesions

How Marcoprim Bolus Works

Once administered, the combination of Sulfamethoxazole and Trimethoprim rapidly enters the bloodstream, reaching infected tissues efficiently. By inhibiting bacterial folate metabolism at two distinct points, Marcoprim Bolus effectively halts bacterial DNA synthesis. This double inhibition results in a bactericidal effect, meaning it kills bacteria instead of merely stopping their growth—leading to faster symptom relief and improved health in infected animals.

Key Features & Benefits

• Broad-Spectrum Action – Effective against a wide range of bacteria
• Faster Recovery – Promotes quicker healing, reducing animal downtime
• Dual Antibiotic Synergy – Enhances antibacterial potency
• Reduces Secondary Infections – Protects animals during vulnerable recovery periods
• Improves Feed Intake – Helps animals regain appetite and energy
• Supports Herd Productivity – Keeps livestock healthy and minimizes economic losses

Side Effects & Precautions
Though well-tolerated, some animals may show:

• Temporary loss of appetite
• Mild gastrointestinal upset (diarrhea or bloating)
• Rare allergic reactions (skin rash or restlessness)

Stop use and contact a vet if any adverse reactions are noticed.

Safety Guidelines
Use only under veterinary supervision

• Do not exceed recommended dosage
• Avoid use in animals allergic to sulfa drugs or trimethoprim
• Not recommended for animals with severe liver or kidney disease
• Avoid concurrent use with other sulfonamides unless prescribed
• Ensure clean drinking water is available during treatment